How to Make It in America follows two enterprising twentysomethings as they hustle their way through New York City, determined to achieve their version of the American Dream. Trying to make a name for themselves in the city's competitive fashion scene, Ben Epstein and his friend and business partner Cam Calderon use their street knowledge and connections to make their way up. With the help of their well-connected friend Domingo and Cam's cousin Rene, who has ambitions of his own - a new high-energy drink called Rasta-Monsta - the burgeoning entrepreneurs set out to make it big.
How to Make It In America stars Bryan Greenberg (Prime, HBO's Unscripted) as Ben, Victor Rasuk (Lords of Dogtown, Raising Victor Vargas) as Cam and Luis Guzman (Anger Management, HBO's OZ) as Rene. Lake Bell (Boston Legal, What Happens in Vegas) stars as Ben's ex-girlfriend Rachel, who is concentrating on her own career as well as a new relationship and hit recording artist Scott "Kid Cudi" Mescudi as Domingo.
The show also stars Martha Plimpton (Beautiful Girls, 200 Cigarettes) as Rachel's boss Edie, an eccentric interior designer; Shannyn Sossamon (40 Days and 40 Nights, The Holiday) as Gingy, Ben and Cam's artsy friend; and Eddie Kaye Thomas (Nick and Norah's Infinite Playlist, American Pie) as David Kaplan, a successful hedge fund manager and high school friend of Ben's.